A Stereoselective Synthesis of Phosphinic Acid Phosphapeptides Corresponding to Glutamyl-γ-glutamate and Incorporation into Potent Inhibitors of Folylpoly-γ-glutamyl Synthetase-Reference-Cited by-同舟云学术

A Stereoselective Synthesis of Phosphinic Acid Phosphapeptides Corresponding to Glutamyl-γ-glutamate and Incorporation into Potent Inhibitors of Folylpoly-γ-glutamyl Synthetase

Published:2005-07-19 Issue:17 Volume:70 Page:6757-6774
ISSN:0022-3263
Container-title:The Journal of Organic Chemistry
language:en
Short-container-title:J. Org. Chem.

Author:

Bartley David M.¹,Coward James K.¹

Affiliation:

1. Departments of Medicinal Chemistry and Chemistry, University of Michigan, Ann Arbor, Michigan, 48109-1055

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/jo0507439

Reference78 articles.

1. McGuire, J. J.; Coward, J. K. InFolates and Pterins; Blakley, R. L., Benkovic, S. J., Eds.; Wiley: New York, 1984; Vol. 1, pp 135−190.

2. Loss of folylpoly-?-glutamate synthetase activity is a dominant mechanism of resistance to polyglutamylation-dependent novel antifolates in multiple human leukemia sublines

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