Synthesis and Evaluation of a Triplex-Forming Oligonucleotide−Pyrrolobenzodiazepine Conjugate
Author:
Affiliation:
1. Arizona Cancer Center, University of Arizona, Tucson, Arizona 85724-5024, James Graham Brown Cancer Center, University of Louisville, Louisville, Kentucky 40202, and Epoch Biosciences, Bothell, Washington 98021.
Publisher
American Chemical Society (ACS)
Subject
Organic Chemistry,Pharmaceutical Science,Pharmacology,Biomedical Engineering,Bioengineering,Biotechnology
Link
https://pubs.acs.org/doi/pdf/10.1021/bc0498673
Reference67 articles.
1. Triplex-forming oligonucleotides: principles and applications
2. Le Doan, T., Perrouault, L., Praseuth, D., Habhoub, N., Decout, J. L., Thuong, N. T., Lhomme, J., and Helene, C. (1987) Sequence-specific recognition, photocrosslinking and cleavage of the dna double helix by an oligo-[alpha]-thymidylate covalently linked to an azidoproflavine derivative.Nucleic Acids Res.15, 7749−7760.
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