Ceftriaxone Blocks the Polymerization of α-Synuclein and Exerts Neuroprotective Effects in Vitro-Reference-Cited by-同舟云学术

Ceftriaxone Blocks the Polymerization of α-Synuclein and Exerts Neuroprotective Effects in Vitro

Published:2013-10-24 Issue:1 Volume:5 Page:30-38
ISSN:1948-7193
Container-title:ACS Chemical Neuroscience
language:en
Short-container-title:ACS Chem. Neurosci.

Author:

Ruzza Paolo¹,Siligardi Giuliano²,Hussain Rohanah²,Marchiani Anna¹,Islami Mehmet¹,Bubacco Luigi³,Delogu Giovanna⁴,Fabbri Davide⁴,Dettori Maria A.⁴,Sechi Mario⁵,Pala Nicolino⁵,Spissu Ylenia⁶,Migheli Rossana⁶,Serra Pier A.⁶,Sechi GianPietro⁶

Affiliation:

1. Institute of Biomolecular Chemistry of CNR, Padua Unit, Padua 35131, Italy

2. Diamond Light Source Ltd., Harwell Science and Innovation Campus, Didcot, Oxfordshire OX11 0DE, United Kingdom

3. Department of Biology, University of Padua, Padua 35121, Italy

4. Institute of Biomolecular Chemistry of CNR, Sassari Unit, Sassari 07100, Italy

5. Department of Chemistry and Pharmacy, University of Sassari, Sassari 07100, Italy

6. Department of Clinical and Experimental Medicine, Medical School, University of Sassari, Sassari 07100, Italy.

Publisher

American Chemical Society (ACS)

Subject

Cell Biology,Cognitive Neuroscience,Physiology,Biochemistry,General Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/cn400149k

Reference41 articles.

1. Passage of cefotaxime and ceftriaxone into cerebrospinal fluid of patients with uninflamed meninges

2. β-Lactam antibiotics offer neuroprotection by increasing glutamate transporter expression

3. In vitro treatments with ceftriaxone promote elimination of mutant glial fibrillary acidic protein and transcription down-regulation

4. Ceftriaxone has a therapeutic role in Alexander disease

5. Ceftriaxone for Alexander’s Disease: A Four-Year Follow-Up

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