1. LCPO-CNRS-ENSCPB-Bordeaux University (UMR 5629)16, Avenue Pey Berland-33607 PESSAC Cedex, France, UEH, Maringa State University, Department of Pharmacy and Pharmacology, CEP 87020-900, Maringa-Parana, Brazil, and CERMAV-CNRS, BP53, 38041 Grenoble Cedex 9, France