Direct Observation of an Enamine Intermediate in Amine Catalysis
Author:
Affiliation:
1. Departments of Chemistry and Molecular Biology and The Skaggs Institute for Chemical Biology, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, California 92037
Publisher
American Chemical Society (ACS)
Subject
Colloid and Surface Chemistry,Biochemistry,General Chemistry,Catalysis
Link
https://pubs.acs.org/doi/pdf/10.1021/ja907271a
Reference22 articles.
1. Efficient Aldolase Catalytic Antibodies That Use the Enamine Mechanism of Natural Enzymes
2. Copying Nature's Mechanism for the Decarboxylation of β-Keto Acids into Catalytic Antibodies by Reactive Immunization
3. Immune Versus Natural Selection: Antibody Aldolases with Enzymic Rates But Broader Scope
4. Antibody-Catalyzed Enantioselective Robinson Annulation
5. Catalytic Enantioselective Retro-Aldol Reactions: Kinetic Resolution ofβ-Hydroxyketones with Aldolase Antibodies
Cited by 61 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献
1. Complete Computational Reaction Mechanism for Foldamer-Catalyzed Aldol Condensation;ACS Catalysis;2024-05-01
2. Enzymatic C─C Bond Formation by Aldol Reactions;Bioorganic and Enzymatic Catalysis;2023-10-20
3. Sculpting a Uniquely Reactive Cysteine Residue for Site-Specific Antibody Conjugation;Bioconjugate Chemistry;2022-05-18
4. An Engineered Arginine Residue of Unusual pH-Sensitive Reactivity Facilitates Site-Selective Antibody Conjugation;Biochemistry;2021-03-23
5. A QM/MM study on the origin of retro-aldolase activity of a catalytic antibody;Chemical Communications;2021
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3