Total Synthesis of Chaetomellic Anhydrides A and B via a Novel Succinate to Maleate Oxidation
Author:
Affiliation:
1. Department of Chemistry, Villanova University, Villanova, Pennsylvania 19085
Publisher
American Chemical Society (ACS)
Subject
Organic Chemistry
Link
https://pubs.acs.org/doi/pdf/10.1021/jo9601977
Reference18 articles.
1. Facile Conversion of Succinic to Maleic-Type Anhydrides, Thioanhydrides, and Imides
2. Isolation and structure of chaetomellic acids A and B from Chaetomella acutiseta: farnesyl pyrophosphate mimic inhibitors of ras farnesyl-protein transferase
3. Chaetomella acutiseta produces chaetomellic acids A and B which are reversible inhibitors of farnesyl-protien transferase
4. Selective inhibition of farnesyl-protein transferase blocks ras processing in vivo.
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1. A Concise Account of the Chemistry of Valuable Alkyl(methyl)maleic Anhydrides;Synthesis;2014-09-26
2. Nickel-Catalyzed Double Carboxylation of Alkynes Employing Carbon Dioxide;Organic Letters;2014-09-08
3. Base-Stimulated 1,2-, 1,4-, and 1,6-Eliminations in Suitably Substituted Alkylidenesuccinates Leading to Natural and Unnatural Conjugated Alkenyl(methyl)maleic Anhydrides;The Journal of Organic Chemistry;2014-03-11
4. Novel route to chaetomellic acid A and analogues: Serendipitous discovery of a more competent FTase inhibitor;Bioorganic & Medicinal Chemistry;2013-01
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