Impact of Absolute Stereochemistry on the Antiangiogenic and Antifungal Activities of Itraconazole
Author:
Affiliation:
1. Department of Pharmacology and Molecular Sciences
2. Medical Scientist Training Program
3. Department of Oncology
Publisher
American Chemical Society (ACS)
Subject
Organic Chemistry,Drug Discovery,Biochemistry
Link
https://pubs.acs.org/doi/pdf/10.1021/ml1000068
Reference16 articles.
1. Inhibition of Angiogenesis by the Antifungal Drug Itraconazole
2. Characteristics of the heterologously expressed human lanosterol 14α-demethylase (other names: P45014DM, CYP51, P45051) and inhibition of the purified human andCandida albicans CYP51 with azole antifungal agents
3. Comparison of lanosterol-14α-demethylase (CYP51) of human and Candida albicans for inhibition by different antifungal azoles
4. STEREOCHEMICAL ASPECTS OF ITRACONAZOLE METABOLISM IN VITRO AND IN VIVO
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