Progress toward the Development of a Safe and Effective Agent for Treating Reentrant Cardiac Arrhythmias: Synthesis and Evaluation of Ibutilide Analogues with Enhanced Metabolic Stability and Diminished Proarrhythmic Potential-Reference-Cited by-同舟云学术

Progress toward the Development of a Safe and Effective Agent for Treating Reentrant Cardiac Arrhythmias: Synthesis and Evaluation of Ibutilide Analogues with Enhanced Metabolic Stability and Diminished Proarrhythmic Potential

Published:2001-03-01 Issue:7 Volume:44 Page:1099-1115
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Hester Jackson B.¹,Gibson John K.¹,Buchanan Lewis V.¹,Cimini Madeline G.¹,Clark Michael A.¹,Emmert D. Edward¹,Glavanovich Michael A.¹,Imbordino Rick J.¹,LeMay Richelle J.¹,McMillan Moses W.¹,Perricone Salvatore C.¹,Squires Donald M.¹,Walters Rodney R.¹

Affiliation:

1. Departments of Structural, Analytical & Medicinal Chemistry, Pharmacology, Biology II, Chemical Processing Research & Preparation, and Pharmacokinetics & Bioanalysis Research, Pharmacia Corporation, Kalamazoo, Michigan 49007

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm0004289

Reference64 articles.

1. Prevalence, Age Distribution, and Gender of Patients With Atrial Fibrillation

2. Impact of Atrial Fibrillation on the Risk of Death

3. The natural history of atrial fibrillation: Incidence, risk factors, and prognosis in the manitoba follow-up study

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