Synthesis and Biological Evaluation of 3,3-Difluoropyridine-2,4(1H,3H)-dione and 3-Deaza-3-fluorouracil Base and Nucleoside Derivatives-Reference-Cited by-同舟云学术

Synthesis and Biological Evaluation of 3,3-Difluoropyridine-2,4(1H,3H)-dione and 3-Deaza-3-fluorouracil Base and Nucleoside Derivatives

Published:2009-04-20 Issue:9 Volume:52 Page:3018-3027
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Robins Morris J.¹,Yang Hong¹,Miranda Karl¹,Peterson Matt A.¹,Clercq Erik De¹,Balzarini Jan¹

Affiliation:

1. Department of Chemistry and Biochemistry, Brigham Young University, Provo, Utah 84602-5700, Rega Institute for Medical Research, Katholieke Universiteit Leuven, B-3000 Leuven, Belgium

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm900203h

Reference28 articles.

1. Deoxygenative [1,2]-Hydride Shift Rearrangements in Nucleoside and Sugar Chemistry: Analogy with the [1,2]-Electron Shift in the Deoxygenation of Ribonucleotides by Ribonucleotide Reductases1

2. The synthesis of 3-deazapyrimidine nucleosides related to uridine and cytidine and their derivatives

3. The synthesis of 3-deazaorotidine and related nucleoside derivatives of 4-hydroxy-2-pyridone

4. A Novel Nucleophilic Displacement of Benzoate by Sulfur During Thiation of 3-Deazauridine Tribenzoate

Cited by 6 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Synthesis and Antioxidative Properties of 1,2,3,4-Tetrahydropyridine Derivatives with Different Substituents in 4-Position;Molecules;2022-11-01

2. Palladium‐Catalyzed Selective Carbofunctionalization of Inert γ‐C( sp 3 )−O Bonds with 4‐Hydroxypyridin‐2( 1H )‐ones and 4‐Hydroxy‐ 2H ‐pyran‐2‐ones;Advanced Synthesis & Catalysis;2020-10-29

3. Synthesis and DABCO‐induced demethylation of 3‐cyano‐4‐methoxy‐2‐pyridone derivatives;Journal of Heterocyclic Chemistry;2019-11-27

4. Comparative evaluation of new dihydropyrimidine and dihydropyridine derivatives perturbing mitotic spindle formation;Future Medicinal Chemistry;2018-10

5. Introduction of a Fluorine Atom at C3 of 3-Deazauridine Shifts Its Antimetabolic Activity from Inhibition of CTP Synthetase to Inhibition of Orotidylate Decarboxylase, an Early Event in the de Novo Pyrimidine Nucleotide Biosynthesis Pathway;Journal of Biological Chemistry;2012-08