Design, Synthesis, and Study of a Mycobactin−Artemisinin Conjugate That Has Selective and Potent Activity against Tuberculosis and Malaria-Reference-Cited by-同舟云学术

Design, Synthesis, and Study of a Mycobactin−Artemisinin Conjugate That Has Selective and Potent Activity against Tuberculosis and Malaria

Published:2011-01-28 Issue:7 Volume:133 Page:2076-2079
ISSN:0002-7863
Container-title:Journal of the American Chemical Society
language:en
Short-container-title:J. Am. Chem. Soc.

Author:

Miller Marvin J.¹,Walz Andrew J.¹,Zhu Helen¹,Wu Chunrui¹,Moraski Garrett¹,Möllmann Ute²,Tristani Esther M.³,Crumbliss Alvin L.³,Ferdig Michael T.⁴,Checkley Lisa⁴,Edwards Rachel L.⁵,Boshoff Helena I.⁵

Affiliation:

1. Department of Chemistry and Biochemistry, University of Notre Dame, 251 Nieuwland Science Hall, Notre Dame, Indiana 46556, United States

2. Leibniz Institute for Natural Product Research and Infection Biology−Hans Knoell Institute, Beutenbergstr. 11a, D-07745 Jena, Germany

3. Department of Chemistry, Duke University, Room 2104, French Family Science Center, 124 Science Drive, Box 90346, Durham, North Carolina 27708, United States

4. Department of Biological Sciences, University of Notre Dame, Notre Dame, Indiana 46556, United States

5. Tuberculosis Research Section, LCID, NIAID, NIH, Room 2W20G, Building 33, MSC 3206, 9000 Rockville Pike, Bethesda, Maryland 20892, United States

Publisher

American Chemical Society (ACS)

Subject

Colloid and Surface Chemistry,Biochemistry,General Chemistry,Catalysis

Link

https://pubs.acs.org/doi/pdf/10.1021/ja109665t

Reference30 articles.

1. Landscapes of Infection

2. World Health Organization. Tuberculosis Web Page.http://www.who.int/tb/publications/factsheets/en/index.html(accessed Nov 8, 2010) and links therein for an overview of tuberculosis worldwide.

3. From magic bullets back to the Magic Mountain: the rise of extensively drug-resistant tuberculosis

4. A small-molecule nitroimidazopyran drug candidate for the treatment of tuberculosis

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