Synthesis of New Acridone Derivatives, Inhibitors of NS3 Helicase, Which Efficiently and Specifically Inhibit Subgenomic HCV Replication-Reference-Cited by-同舟云学术

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Synthesis of New Acridone Derivatives, Inhibitors of NS3 Helicase, Which Efficiently and Specifically Inhibit Subgenomic HCV Replication

Published:2010-03-25 Issue:8 Volume:53 Page:3117-3126
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Stankiewicz-Drogoń Anna¹,Dörner Bernd²,Erker Thomas²,Boguszewska-Chachulska Anna M.³⁴

Affiliation:

1. Institute of Biochemistry and Biophysics, PAS, Pawinskiego 5a, 02-106 Warsaw, Poland

2. University of Vienna, Department of Medicinal Chemistry, Althanstrasse 14, 1090 Vienna, Austria

3. Genomed, Ponczowa 12, 02-971 Warsaw, Poland

4. Warsaw University of Technology, Faculty of Chemistry, Noakowskiego 3, 00-664 Warsaw, Poland

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm901741p

Reference33 articles.

1. Antiviral therapy for chronic hepatitis C: past, present, and future

2. Rapid Decline of Viral RNA in Hepatitis C Patients Treated With VX-950: A Phase Ib, Placebo-Controlled, Randomized Study

3. Manns, M.; Muir, A.; Adda, N.; et al.Telaprevir in hepatitis C genotype-1-infected patients with prior non-response, viral breakthrough or relapse to peginterferon-alfa-2a/b and ribavirin therapy: SVR results of the PROVE3 study. In44th Annual Meeting of the European Association for the Study of the Liver (EASL 2009),Copenhagen,2009.

4. Kwo, P.; Lawitz, E.; McCone, J.; Schiff, E.; Vierling, J.; Pound, D.; Davis, M.; Galati, J.; Gordon, S.; Ravendhran, N.; Rossaro, L.; Anderson, F.; Jacobson, I.; Rubin, R.; Koury, K.; Brass, C.; Chaudhri, E.; Albrecht, J.HCV SPRINT-1 final results: SVR 24 from a phase 2 study of boceprevir plus pegintron (peginterferon alfa-2b)/ribavirin in treatment-naïve subjects with genotype-1 chronic hepatitis C. In44th Annual Meeting of the European Association for the Study of the Liver (EASL),Copenhagen,2009.

5. Directly acting antivirals for the treatment of patients with hepatitis C infection: A clinical development update addressing key future challenges

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2. Synthesis and spectroscopic studies of some new 4-amino-7-nitro acridin 9 (10H) one Schiff base complexes;2ND INTERNATIONAL CONFERENCE OF MATHEMATICS, APPLIED SCIENCES, INFORMATION AND COMMUNICATION TECHNOLOGY;2023

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4. Direct Observation of Ultrafast Access to a Solvent-Independent Singlet–Triplet Equilibrium State in Acridone Solutions;The Journal of Physical Chemistry B;2021-11-27

5. Сationic carboxamide derivatives of tricyclic heteroaromatic compounds: synthesis and preliminary evaluation of antiproliferative activity;Ukr. Bioorg. Acta 2020, Vol. 15, N1;2020-06-30

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