Imidazolylmethylbenzophenones as Highly Potent Aromatase Inhibitors
Author:
Affiliation:
1. Department of Pharmaceutical Sciences, University of Bologna, Via Belmeloro, 6, I-40126 Bologna, Italy, and Pharmaceutical and Medicinal Chemistry, Saarland University, Post Office Box 151150, D-66041 Saarbrücken, Germany
Publisher
American Chemical Society (ACS)
Subject
Drug Discovery,Molecular Medicine
Link
https://pubs.acs.org/doi/pdf/10.1021/jm0702938
Reference21 articles.
1. New developments in the treatment of postmenopausal breast cancer
2. Aromatase Inhibitors in the Treatment of Breast Cancer
3. Phase III Study of Letrozole Versus Tamoxifen as First-Line Therapy of Advanced Breast Cancer in Postmenopausal Women: Analysis of Survival and Update of Efficacy From the International Letrozole Breast Cancer Group
4. Potent CYP19 (Aromatase) 1-[(Benzofuran-2-yl)(phenylmethyl)pyridine, -imidazole, and -triazole Inhibitors: Synthesis and Biological Evaluation
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