Discrimination of 5‘-GGGG-3‘, 5‘-GCGC-3‘, and 5‘-GGCC-3‘ Sequences in the Minor Groove of DNA by Eight-Ring Hairpin Polyamides
Author:
Affiliation:
1. Contribution from the Division of Chemistry and Chemical Engineering, California Institute of Technology, Pasadena, California 91125
Publisher
American Chemical Society (ACS)
Subject
Colloid and Surface Chemistry,Biochemistry,General Chemistry,Catalysis
Link
https://pubs.acs.org/doi/pdf/10.1021/ja971184t
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1. Recognition of DNA by designed ligands at subnanomolar concentrations
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3. Antiparallel side-by-side dimeric motif for sequence-specific recognition in the minor groove of DNA by the designed peptide 1-methylimidazole-2-carboxamide netropsin.
4. Binding affinities of synthetic peptides, pyridine-2-carboxamidonetropsin and 1-methylimidazole-2-carboxamidonetropsin, that form 2:1 complexes in the minor groove of double-helical DNA
5. Structural characterization of a 2:1 distamycin A.d(CGCAAATTGGC) complex by two-dimensional NMR.
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