Optimization of Search Engines and Postprocessing Approaches to Maximize Peptide and Protein Identification for High-Resolution Mass Data

Author:

Tu Chengjian12,Sheng Quanhu3,Li Jun12,Ma Danjun4,Shen Xiaomeng12,Wang Xue125,Shyr Yu3,Yi Zhengping4,Qu Jun12

Affiliation:

1. Department of Pharmaceutical Sciences, State University of New York, 285 Kapoor Hall, Buffalo, New York 14260, United States

2. New York State Center of Excellence in Bioinformatics and Life Sciences, 701 Ellicott Street, Buffalo, New York 14203, United States

3. Center for Quantitative Sciences, Vanderbilt University School of Medicine, 2220 Pierce Avenue, Nashville, Tennessee 37232, United States

4. Department of Pharmaceutical Sciences, Eugene Applebaum College of Pharmacy/Health Sciences, Wayne State University, 259 Mack Avenue, Detroit, Michigan 48202, United States

5. Department of Cell Stress Biology, Roswell Park Cancer Institute, Elm and Carlton Streets, Buffalo, New York 14263, United States

Funder

American Heart Association

Center for Protein Therapeutics, University at Buffalo

National Institute of Diabetes and Digestive and Kidney Diseases

National Heart, Lung, and Blood Institute

National Institute of Child Health and Human Development

Publisher

American Chemical Society (ACS)

Subject

General Chemistry,Biochemistry

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