Multi-omic Analyses Reveal Minimal Impact of the CRISPR-Cas9 Nuclease on Cultured Human Cells

Author:

Qiang Jiali12ORCID,Ma Zaijun12ORCID,Xie Xingxing12,Shi Linyu13ORCID,Geng Yang1,Hu Junhao1,Liu Rui4,Liu Nan1,Zhang Yaoyang1ORCID

Affiliation:

1. Interdisciplinary Research Center on Biology and Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, 26 Qiuyue Road, Pudong, Shanghai 201210, China

2. University of Chinese Academy of Sciences, Beijing 100049, China

3. Institute of Neuroscience, State Key Laboratory of Neuroscience, Key Laboratory of Primate Neurobiology, CAS Center for Excellence in Brain Science and Intelligence Technology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai 200031, China

4. Singlera Genomics, 781 Cailun Road, Rm 1208, Pudong, Shanghai 201203, China

Funder

Ministry of Science and Technology of the People's Republic of China

National Natural Science Foundation of China

Chinese Academy of Sciences

Publisher

American Chemical Society (ACS)

Subject

General Chemistry,Biochemistry

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