Mild Acid Elution and MHC Immunoaffinity Chromatography Reveal Similar Albeit Not Identical Profiles of the HLA Class I Immunopeptidome

Author:

Sturm Theo1234ORCID,Sautter Benedikt5,Wörner Tobias P.23,Stevanović Stefan5,Rammensee Hans-Georg5,Planz Oliver5,Heck Albert J. R.23ORCID,Aebersold Ruedi16

Affiliation:

1. Institute of Molecular Systems Biology, Department of Biology, ETH Zürich, 8093 Zürich, Switzerland

2. Biomolecular Mass Spectrometry and Proteomics, Bijvoet Center for Biomolecular Research and Utrecht Institute for Pharmaceutical Sciences, Utrecht University, 3584 CH Utrecht, The Netherlands

3. Netherlands Proteomics Centre, 3584 CH Utrecht, The Netherlands

4. Philochem AG, 8112 Otelfingen, Switzerland

5. Department of Immunology, Institute for Cell Biology, University of Tübingen, 72076 Tübingen, Germany

6. Faculty of Science, University of Zurich, 8057 Zürich, Switzerland

Funder

Schweizerischer Nationalfonds zur F?rderung der Wissenschaftlichen Forschung

H2020 Future and Emerging Technologies

Horizon 2020 Framework Programme

H2020 European Research Council

Nederlandse Organisatie voor Wetenschappelijk Onderzoek

Publisher

American Chemical Society (ACS)

Subject

General Chemistry,Biochemistry

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