Smelling the Dark Proteome: Functional Characterization of PITH Domain-Containing Protein 1 (C1orf128) in Olfactory Metabolism

Author:

Lachén-Montes Mercedes123,Mendizuri Naroa123,Ausín Karina123,Pérez-Mediavilla Alberto34,Azkargorta Mikel5,Iloro Ibon5,Elortza Felix5,Kondo Hiroyuki6,Ohigashi Izumi6,Ferrer Isidre78910,de la Torre Rafael11121314,Robledo Patricia1112,Fernández-Irigoyen Joaquín123,Santamaría Enrique123ORCID

Affiliation:

1. Clinical Neuroproteomics Unit, Navarrabiomed, Complejo Hospitalario de Navarra (CHN), Universidad Pública de Navarra (UPNA), Irunlarrea 3, 31008 Pamplona, Spain

2. Proteored-ISCIII, Proteomics Platform, Navarrabiomed, Complejo Hospitalario de Navarra (CHN), Universidad Pública de Navarra (UPNA), Irunlarrea 3, 31008 Pamplona, Spain

3. IdiSNA, Navarra Institute for Health Research, Irunlarrea 3, 31008 Pamplona, Spain

4. Neurobiology of Alzheimer’s Disease, Department of Biochemistry, Center for Applied Medical Research (CIMA), Neurosciences Division, University of Navarra, 31008 Pamplona, Spain

5. Proteomics Platform, CIC bioGUNE, CIBERehd, ProteoRed-ISCIII, Bizkaia Science and Technology Park, 48160 Derio, Spain

6. Division of Experimental Immunology, Institute of Advanced Medical Sciences, Tokushima University, Tokushima 770-8503, Japan

7. Bellvitge Biomedical Research Institute (IDIBELL), 08908 Hospitalet de Llobregat, Spain

8. CIBERNED (Network Centre of Biomedical Research of Neurodegenerative Diseases), Institute of Health Carlos III, 28029 Madrid, Spain

9. Department of Pathology and Experimental Therapeutics, University of Barcelona, 08908 Hospitalet de Llobregat, Spain

10. Institute of Neurosciences, University of Barcelona, 08007 Barcelona, Spain

11. Integrative Pharmacology and Systems Neuroscience Research Group, Neurosciences Research Program, IMIM (Hospital del Mar Medical Research Institute), 08003 Barcelona, Spain

12. Department of Experimental and Health Sciences, Pompeu Fabra University (CEXS-UPF), 08002 Barcelona, Spain

13. School of Medicine, Universitat Autònoma de Barcelona, 08193 Cerdanyola del Vallès, Spain

14. CIBER de Fisiopatología de la Obesidad y Nutrición (CB06/03), CIBEROBN, 28029 Madrid, Spain

Funder

Takeda Science Foundation

Ministerio de Ciencia e Innovaci?n

Instituto de Salud Carlos III

Department of Economic and Business Development from Government of Navarra

Publisher

American Chemical Society (ACS)

Subject

General Chemistry,Biochemistry

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