Moving Pieces in a Cellular Puzzle: A Cryptic Peptide from the Scorpion Toxin Ts14 Activates AKT and ERK Signaling and Decreases Cardiac Myocyte Contractility via Dephosphorylation of Phospholamban

Author:

Goméz-Mendoza Diana P.1,Lemos Rafael Pereira1,Jesus Itamar C. G.1,Gorshkov Vladimir2ORCID,McKinnie Shaun M. K.3ORCID,Vederas John C.3,Kjeldsen Frank2ORCID,Guatimosim Silvia1,Santos Robson Augusto1,Pimenta Adriano M. C.4,Verano-Braga Thiago1ORCID

Affiliation:

1. Departamento de Fisiologia e Biofisica, Universidade Federal de Minas Gerais, Belo Horizonte 31270-901, Brazil

2. Department of Biochemistry and Molecular Biology, University of Southern Denmark, Odense 5230, Denmark

3. Department of Chemistry, University of Alberta, Edmonton, Alberta T6G 2G2, Canada

4. Departamento de Bioquimica e Imunologia, Universidade Federal de Minas Gerais, Belo Horizonte 31270-901, Brazil

Funder

Funda??o de Amparo ? Pesquisa do Estado de Minas Gerais

Conselho Nacional de Desenvolvimento Cient?fico e Tecnol?gico

Coordena??o de Aperfei?oamento de Pessoal de N?vel Superior

Publisher

American Chemical Society (ACS)

Subject

General Chemistry,Biochemistry

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