Quantitative Proteomics Combined with Two Genetic Strategies for Screening Substrates of Ubiquitin Ligase Hrt3-Reference-Cited by-同舟云学术

Quantitative Proteomics Combined with Two Genetic Strategies for Screening Substrates of Ubiquitin Ligase Hrt3

Published:2019-12-01 Issue:1 Volume:19 Page:493-502
ISSN:1535-3893
Container-title:Journal of Proteome Research
language:en
Short-container-title:J. Proteome Res.

Author:

Lan Qiuyan¹²,Wang Yihao²³,Sun Zhen²,Li Yanchang²^ORCID,Zhang Cheng¹,Chang Lei²,Gao Yue³,Wu Junzhu¹,Wang Fuqiang²,Xu Ping¹²⁴⁵^ORCID

Affiliation:

1. School of Basic Medical Science, Key Laboratory of Combinatorial Biosynthesis and Drug Discovery of Ministry of Education, School of Pharmaceutical Sciences, Wuhan University, Wuhan 430071, P. R. China

2. State Key Laboratory of Proteomics, Beijing Proteome Research Center, National Center for Protein Sciences (Beijing), Beijing Institute of Lifeomics, Beijing 102206, P. R. China

3. Department of Pharmacology and Toxicology, Beijing Institute of Radiation Medicine, Beijing 100850, P. R. China

4. Second Clinical Medicine College, Guangzhou University Chinese Medicine, Guangzhou 510120, P. R. China

5. Research Unit of Proteomics & Research and Development of New Drug, Chinese Academy of Medical Sciences, Beijing 100730, P. R. China

Funder

Ministry of Science and Technology of the People's Republic of China

National Natural Science Foundation of China

Unilevel 21th Century Toxicity Program

State Key Lab of Proteomics, Beijing Institute of Radiation Medicine, Academy of Military Medical Sciences

Guangzhou science and technology innovation and development project

Innovation Foundation of Medicine

Publisher

American Chemical Society (ACS)

Subject

General Chemistry,Biochemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jproteome.9b00673

Reference40 articles.

1. Diversity of degradation signals in the ubiquitin–proteasome system

2. Ufd2p synthesizes branched ubiquitin chains to promote the degradation of substrates modified with atypical chains

3. K63 ubiquitylation triggers proteasomal degradation by seeding branched ubiquitin chains

4. Atypical ubiquitylation — the unexplored world of polyubiquitin beyond Lys48 and Lys63 linkages

5. Principles of Ubiquitin-Dependent Signaling

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