Prepregnant Obesity of Mothers in a Multiethnic Cohort Is Associated with Cord Blood Metabolomic Changes in Offspring

Author:

Schlueter Ryan J.1,Al-Akwaa Fadhl M.2ORCID,Benny Paula A.3,Gurary Alexandra4,Xie Guoxiang5,Jia Wei5ORCID,Chun Shaw J.3,Chern Ingrid1,Garmire Lana X.2

Affiliation:

1. Department of Obstetrics and Gynecology, University of Hawaii, 1319 Punahou St Ste 824, Honolulu, Hawaii 96826, United States

2. Department of Computational Medicine and Bioinformatics, North Campus Research Complex, University of Michigan, 1600 Huron Parkway, Ann Arbor, Michigan 48105, United States

3. Department of Epidemiology, University of Hawaii Cancer Center, 701 Ilalo Street, Honolulu, Hawaii 96813, United States

4. John A. Burns School of Medicine, Department of Tropical Medicine, Medical Microbiology and Pharmacology, University of Hawaii, 651 Ilalo Street, Bioscience Building 320, Honolulu, Hawaii 96813, United States

5. Metabolomics Shared Resource, University of Hawaii Cancer Center, 701 Ilalo Street, Honolulu, Hawaii 96813, United States

Funder

U.S. Department of Health and Human Services

Department of Obstetrics and Gynecology, University of Hawaii

Publisher

American Chemical Society (ACS)

Subject

General Chemistry,Biochemistry

Reference64 articles.

1. Prevalence of Obesity and Trends in the Distribution of Body Mass Index Among US Adults, 1999-2010

2. Ogden, C. L.; Carroll, M. D.; Kit, B. K.; Flegal, K. M. Prevalence of obesity in the United States, 2009-2010. NCHS Data Brief, 2012; (82), pp 1–8.

3. Branum, A.; Kirmeyer, S. E.; Gregory, E. C. W. Prepregnancy Body Mass Index by Maternal Characteristics and State: Data from the Birth Certificate, 2014, 2016; pp 1–11.

4. Epigenetic and developmental influences on the risk of obesity, diabetes, and metabolic syndrome

5. Fetal origins of coronary heart disease

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