Chimeric Agents Derived from the Functionalized Amino Acid, Lacosamide, and the α-Aminoamide, Safinamide: Evaluation of Their Inhibitory Actions on Voltage-Gated Sodium Channels, and Antiseizure and Antinociception Activities and Comparison with Lacosamide and Safinamide-Reference-Cited by-同舟云学术

Chimeric Agents Derived from the Functionalized Amino Acid, Lacosamide, and the α-Aminoamide, Safinamide: Evaluation of Their Inhibitory Actions on Voltage-Gated Sodium Channels, and Antiseizure and Antinociception Activities and Comparison with Lacosamide and Safinamide

Published:2014-12-09 Issue:2 Volume:6 Page:316-330
ISSN:1948-7193
Container-title:ACS Chemical Neuroscience
language:en
Short-container-title:ACS Chem. Neurosci.

Author:

Park Ki Duk,Yang Xiao-Fang¹,Dustrude Erik T.,Wang Yuying¹,Ripsch Matthew S.,White Fletcher A.,Khanna Rajesh¹,Kohn Harold²

Affiliation:

1. Department of Pharmacology and Neuroscience Graduate Interdisciplinary Program, College of Medicine, University of Arizona, Tucson, Arizona 85742, United States

2. NeuroGate Therapeutics, Inc., 150 Fayetteville Street, Suite 2300, Raleigh, North Carolina 27601, United States

Funder

National Institute of Neurological Disorders and Stroke

American Heart Association

Publisher

American Chemical Society (ACS)

Subject

Cell Biology,Cognitive Neuroscience,Physiology,Biochemistry,General Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/cn5002182

Reference52 articles.

1. Merging the Structural Motifs of Functionalized Amino Acids and α-Aminoamides: Compounds with Significant Anticonvulsant Activities