Identification of 1,5-Naphthyridine Derivatives as a Novel Series of Potent and Selective TGF-β Type I Receptor Inhibitors-Reference-Cited by-同舟云学术

Identification of 1,5-Naphthyridine Derivatives as a Novel Series of Potent and Selective TGF-β Type I Receptor Inhibitors

Published:2004-08-01 Issue:18 Volume:47 Page:4494-4506
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Gellibert Françoise¹,Woolven James¹,Fouchet Marie-Hélène¹,Mathews Neil¹,Goodland Helen¹,Lovegrove Victoria¹,Laroze Alain¹,Nguyen Van-Loc¹,Sautet Stéphane¹,Wang Ruolan¹,Janson Cheryl¹,Smith Ward¹,Krysa Gaël¹,Boullay Valérie¹,de Gouville Anne-Charlotte¹,Huet Stéphane¹,Hartley David¹

Affiliation:

1. Departments of Medicinal Chemistry and Biology, GlaxoSmithKline, 25-27 Avenue du Québec, 91951 Les Ulis, France, Discovery Research, Computational and Structural Science, and Department of Medicinal Chemistry, GlaxoSmithKline, Gunnels Wood Road, Stevenage, Hertfordshire SG1 2NY, United Kingdom, Discovery Research, Assay Development and Compound Profiling, GlaxoSmithKline, Five Moore Drive, P.O. Box 13398, Research Triangle Park, North Carolina 27709, and Discovery Research, GlaxoSmithKline, 709 Swedeland...

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm0400247

Reference28 articles.

1. TGFβ Signaling in Growth Control, Cancer, and Heritable Disorders

2. Role of Transforming Growth Factor β in Human Disease

3. Transforming Growth Factor β as a Predictor of Liver and Lung Fibrosis after Autologous Bone Marrow Transplantation for Advanced Breast Cancer

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