Synthesis and Biological Evaluation of Novel Pyrazoles and Indazoles as Activators of the Nitric Oxide Receptor, Soluble Guanylate Cyclase-Reference-Cited by-同舟云学术

Synthesis and Biological Evaluation of Novel Pyrazoles and Indazoles as Activators of the Nitric Oxide Receptor, Soluble Guanylate Cyclase

Published:2000-11-22 Issue:1 Volume:44 Page:78-93
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Selwood David L.¹,Brummell David G.¹,Budworth Joanna¹,Burtin Guillaume E.¹,Campbell Richard O.¹,Chana Surinder S.¹,Charles Ian G.¹,Fernandez Patricia A.¹,Glen Robert C.¹,Goggin Maria C.¹,Hobbs Adrian J.¹,Kling Marcel R.¹,Liu Qian¹,Madge David J.¹,Meillerais Sylvie¹,Powell Kenneth L.¹,Reynolds Karen¹,Spacey Graham D.¹,Stables Jeremy N.¹,Tatlock Mark A.¹,Wheeler Kerry A.¹,Wishart Grant¹,Woo Chi-Kit¹

Affiliation:

1. Biological & Medicinal Chemistry and Molecular & Cellular Biology, The Wolfson Institute for Biomedical Research, University College London, The Cruciform Building, Gower Street, London WC1E 6BT, U.K., and Tripos Inc., 1699 South Hanley Road, St. Louis, Missouri 63144

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm001034k

Reference46 articles.

1. Soluble guanylate cyclase: the forgotten sibling

2. A Major Role for Prostacyclin in Nitric Oxide–Induced Ocular Vasorelaxation in the Piglet

3. Regeneration of the Ferrous Heme of Soluble Guanylate Cyclase from the Nitric Oxide Complex: Acceleration by Thiols and Oxyhemoglobin

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