Development of Organometallic S6K1 Inhibitors-Reference-Cited by-同舟云学术

Development of Organometallic S6K1 Inhibitors

Published:2014-11-13 Issue:1 Volume:58 Page:305-314
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Qin Jie¹,Rajaratnam Rajathees²,Feng Li²,Salami Jemilat¹,Barber-Rotenberg Julie S.¹³,Domsic John¹³,Reyes-Uribe Patricia¹,Liu Haiying⁴,Dang Weiwei⁴,Berger Shelley L.³,Villanueva Jessie¹,Meggers Eric²,Marmorstein Ronen¹³

Affiliation:

1. The Wistar Institute, 3601 Spruce Street, Philadelphia, Pennsylvania 19104, United States

2. Philipps-Universität Marburg, Hans-Meerwein-Strasse, 35043 Marburg, Germany

3. Perelman School of Medicine, University of Pennsylvania, 421 Curie Boulevard, Philadelphia, Pennsylvania 19104, United States

4. Huffington Center on Aging, Baylor College of Medicine, Houston, Texas 77030, United States

Funder

National Cancer Institute

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm5011868

Reference40 articles.

1. 3-Phosphoinositide-dependent protein kinase 1 (PDK1) phosphorylates and activates the p70 S6 kinase in vivo and in vitro

2. Control of p70 S6 kinase by kinase activity of FRAP in vivo

3. Rapamycin suppresses 5'TOP mRNA translation through inhibition of p70s6k

4. The 70 kDa S6 kinase: regulation of a kinase with multiple roles in mitogenic signalling

5. Drosophila S6 Kinase: A Regulator of Cell Size

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