2-Aryl-2,2-difluoroacetamide FKBP12 Ligands: Synthesis and X-ray Structural Studies-Reference-Cited by-同舟云学术

2-Aryl-2,2-difluoroacetamide FKBP12 Ligands: Synthesis and X-ray Structural Studies

Published:2001-11-17 Issue:25 Volume:3 Page:3987-3990
ISSN:1523-7060
Container-title:Organic Letters
language:en
Short-container-title:Org. Lett.

Author:

Dubowchik Gene M.¹,Vrudhula Vivekananda M.¹,Dasgupta Bireshwar¹,Ditta Jonathan¹,Chen Ti¹,Sheriff Steven¹,Sipman Karin¹,Witmer Mark¹,Tredup Jeffrey¹,Vyas Dolatrai M.¹,Verdoorn Todd A.¹,Bollini Sagarika¹,Vinitsky Alexander¹

Affiliation:

1. Bristol-Myers Squibb Pharmaceutical Research Institute, P.O. Box 5100, Wallingford, Connecticut 06492-7660, and P.O. Box 4000, Princeton, New Jersey 08543-4000

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/ol0166909

Reference27 articles.

1. Peptidylproline cis-trans-isomerases: immunophilins

2. Chemistry and Biology of the Immunophilins and Their Immunosuppressive Ligands

3. FKBP12 Binding Modulates Ryanodine Receptor Channel Gating

4. Crystal Structure of the Cytoplasmic Domain of the Type I TGF β Receptor in Complex with FKBP12

5. Neuronal regeneration enhances the expression of the immunophilin FKBP- 12

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