Evaluation of Difluoromethyl Ketones as Agonists of the γ-Aminobutyric Acid Type B (GABAB) Receptor-Reference-Cited by-同舟云学术

Evaluation of Difluoromethyl Ketones as Agonists of the γ-Aminobutyric Acid Type B (GABAB) Receptor

Published:2013-03-06 Issue:6 Volume:56 Page:2456-2465
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Han Changho¹,Salyer Amy E.¹,Kim Eun Hoo¹,Jiang Xinyi¹,Jarrard Rachel E.¹,Powers Matthew S.²,Kirchhoff Aaron M.²,Salvador Tolani K.³,Chester Julia A.²,Hockerman Gregory H.¹,Colby David A.¹³

Affiliation:

1. Department of Medicinal Chemistry and Molecular Pharmacology, Purdue University, West Lafayette, Indiana 47907, United States

2. Department of Psychological Sciences, Purdue University, West Lafayette, Indiana 47907, United States

3. Department of Chemistry, Purdue University, West Lafayette, Indiana 47907, United States

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm301805e

Reference48 articles.

1. International Union of Pharmacology. LXX. Subtypes of γ-Aminobutyric AcidAReceptors: Classification on the Basis of Subunit Composition, Pharmacology, and Function. Update

2. Structural Requirements for Eszopiclone and Zolpidem Binding to the γ-Aminobutyric Acid Type-A (GABAA) Receptor Are Different

3. GABAB receptors: synaptic functions and mechanisms of diversity

4. Historical Perspective and Emergence of the GABAB Receptor

5. Evidence for association of GABABreceptors with Kir3 channels and regulators of G protein signalling (RGS4) proteins

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