Facile and Selective Electrostatic Stabilization of Uracil N(1)- Anion by a Proximate Protonated Amine: A Chemical Implication for Why Uracil N(1) Is Chosen for Glycosylation Site-Reference-Cited by-同舟云学术

Facile and Selective Electrostatic Stabilization of Uracil N(1)- Anion by a Proximate Protonated Amine: A Chemical Implication for Why Uracil N(1) Is Chosen for Glycosylation Site

Published:1997-11-01 Issue:45 Volume:119 Page:10909-10919
ISSN:0002-7863
Container-title:Journal of the American Chemical Society
language:en
Short-container-title:J. Am. Chem. Soc.

Author:

Kimura Eiichi¹,Kitamura Hideyuki¹,Koike Tohru¹,Shiro Motoo¹

Affiliation:

1. Contribution from the Department of Medicinal Chemistry, School of Medicine, Hiroshima University, Kasumi 1-2-3, Minami-ku, Hiroshima, 734, Japan, and Rigaku Corporation X-ray Research Laboratory, Matsubaracho 3-9-12, Akishima, Tokyo, 196, Japan

Publisher

American Chemical Society (ACS)

Subject

Colloid and Surface Chemistry,Biochemistry,General Chemistry,Catalysis

Link

https://pubs.acs.org/doi/pdf/10.1021/ja972129n

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1. Low-Barrier Hydrogen Bonds and Enzymic Catalysis

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5. The structural basis of specific base-excision repair by uracil–DNA glycosylase

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