Hypoxanthine Guanine Phosphoribosyltransferase Distorts the Purine Ring of Nucleotide Substrates and Perturbs the pKa of Bound Xanthosine Monophosphate-Reference-Cited by-同舟云学术

Hypoxanthine Guanine Phosphoribosyltransferase Distorts the Purine Ring of Nucleotide Substrates and Perturbs the pKa of Bound Xanthosine Monophosphate

Published:2011-04-25 Issue:19 Volume:50 Page:4184-4193
ISSN:0006-2960
Container-title:Biochemistry
language:en
Short-container-title:Biochemistry

Author:

Gogia Spriha¹,Balaram Hemalatha²,Puranik Mrinalini¹

Affiliation:

1. National Centre for Biological Sciences, TIFR, GKVK Campus, Bellary Road, Bangalore 560065, India

2. Jawaharlal Nehru Centre for Advanced Scientific Research, Jakkur, Bangalore 560064, India

Publisher

American Chemical Society (ACS)

Subject

Biochemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/bi102039b

Reference30 articles.

1. Purine metabolism in the schistosomes: Potential targets for chemotherapy

2. Purine salvage in Schistosoma mansoni schistosomules

3. A non-active site mutation in human hypoxanthine guanine phosphoribosyltransferase expands substrate specificity

4. Purification and characterization of Plasmodium falciparum hypoxanthine–guanine–xanthine phosphoribosyltransferase and comparison with the human enzyme

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