Diazine Indole Acetic Acids as Potent, Selective, and Orally Bioavailable Antagonists of Chemoattractant Receptor Homologous Molecule Expressed on Th2 Cells (CRTH2) for the Treatment of Allergic Inflammatory Diseases
Author:
Affiliation:
1. BioTherapeutics Chemistry, Pfizer Worldwide Medicinal Chemistry, 200 Cambridgepark Drive, Cambridge, Massachusetts 02140, United States
Publisher
American Chemical Society (ACS)
Subject
Drug Discovery,Molecular Medicine
Link
https://pubs.acs.org/doi/pdf/10.1021/jm300007n
Reference49 articles.
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3. Emerging roles of DP and CRTH2 in allergic inflammation
4. CRTH2: marker for the detection of human Th2 and Tc2 cells
5. Advances in eicosanoid research, novel therapeutic implications
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