Catalytic Core of Human Topoisomerase IIα: Insights into Enzyme–DNA Interactions and Drug Mechanism
Author:
Affiliation:
1. Department of Pharmaceutical Sciences, Lipscomb University College of Pharmacy, Nashville, Tennessee 37204-3951, United States
2. VA Tennessee Valley Healthcare System, Nashville, Tennessee 37212, United States
Funder
Directorate for Biological Sciences
National Cancer Institute
National Institute of General Medical Sciences
Publisher
American Chemical Society (ACS)
Subject
Biochemistry
Link
https://pubs.acs.org/doi/pdf/10.1021/bi5010816
Reference60 articles.
1. The why and how of DNA unlinking
2. The DNA cleavage reaction of topoisomerase II: wolf in sheep's clothing
3. DNA topoisomerase II and its growing repertoire of biological functions
4. DNA Topoisomerases and Their Poisoning by Anticancer and Antibacterial Drugs
5. All tangled up: how cells direct, manage and exploit topoisomerase function
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