Deoxyribonucleoside Cyclic N-Acylphosphoramidites as a New Class of Monomers for the Stereocontrolled Synthesis of Oligothymidylyl- and Oligodeoxycytidylyl- Phosphorothioates-Reference-Cited by-同舟云学术

Deoxyribonucleoside Cyclic N-Acylphosphoramidites as a New Class of Monomers for the Stereocontrolled Synthesis of Oligothymidylyl- and Oligodeoxycytidylyl- Phosphorothioates

Published:2000-02-24 Issue:10 Volume:122 Page:2149-2156
ISSN:0002-7863
Container-title:Journal of the American Chemical Society
language:en
Short-container-title:J. Am. Chem. Soc.

Author:

Wilk Andrzej¹,Grajkowski Andrzej¹,Phillips Lawrence R.¹,Beaucage Serge L.¹

Affiliation:

1. Contribution from the Division of Therapeutic Proteins, Center for Biologics Evaluation and Research, Food and Drug Administration, 8800 Rockville Pike, Bethesda, Maryland 20892, and Laboratory of Drug Discovery Research and Development, Developmental Therapeutics Program, National Cancer Institute, Frederick, Maryland 21701

Publisher

American Chemical Society (ACS)

Subject

Colloid and Surface Chemistry,Biochemistry,General Chemistry,Catalysis

Link

https://pubs.acs.org/doi/pdf/10.1021/ja991773u

Reference47 articles.

1. Progress in Antisense Oligonucleotide Therapeutics

2. Analysis of oligo(deoxynucleoside phosphorothioate)s and their diastereomeric composition

3. Stereo-Reproducibility of the Phosphoramidite Method in the Synthesis of Oligonucleotide Phosphorothioates

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