The 3-(N-tert-Butylcarboxamido)-1-propyl Group as an Attractive Phosphate/Thiophosphate Protecting Group for Solid-Phase Oligodeoxyribonucleotide Synthesis-Reference-Cited by-同舟云学术

The 3-(N-tert-Butylcarboxamido)-1-propyl Group as an Attractive Phosphate/Thiophosphate Protecting Group for Solid-Phase Oligodeoxyribonucleotide Synthesis

Published:2002-08-15 Issue:18 Volume:67 Page:6430-6438
ISSN:0022-3263
Container-title:The Journal of Organic Chemistry
language:en
Short-container-title:J. Org. Chem.

Author:

Wilk Andrzej¹,Chmielewski Marcin K.¹,Grajkowski Andrzej¹,Phillips Lawrence R.¹,Beaucage Serge L.¹

Affiliation:

1. Division of Therapeutic Proteins, Center for Biologics Evaluation and Research, Food and Drug Administration, 8800 Rockville Pike, Bethesda, Maryland 20892, and Biological Testing Branch, Developmental Therapeutics Program, National Cancer Institute, Frederick, Maryland 21701

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/jo0258608

Reference29 articles.

1. Deoxynucleoside phosphoramidites—A new class of key intermediates for deoxypolynucleotide synthesis

2. Polymer support oligonucleotide synthesis XVIII1.2): use ofβ-cyanoethyi-N,N-dialkylamino-/N-morpholino phosphoramidite of deoxynucleosides for the synthesis of DNA fragments simplifying deprotection and isolation of the final product

3. Advances in the Synthesis of Oligonucleotides by the Phosphoramidite Approach

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