Synthesis and Biological Evaluation of Novel 9-Substituted-8-Hydroxyadenine Derivatives as Potent Interferon Inducers-Reference-Cited by-同舟云学术

Synthesis and Biological Evaluation of Novel 9-Substituted-8-Hydroxyadenine Derivatives as Potent Interferon Inducers

Published:2006-02-15 Issue:6 Volume:49 Page:2088-2095
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Isobe Yoshiaki¹,Kurimoto Ayumu¹,Tobe Masanori¹,Hashimoto Kazuki¹,Nakamura Tomoaki¹,Norimura Kei¹,Ogita Haruhisa¹,Takaku Haruo¹

Affiliation:

1. Chemistry Research Laboratories and Discovery Research Laboratories II, Dainippon Sumitomo Pharmaceuticals Company Ltd., 1-98, Kasugade Naka, 3-chome, Konohana-ku, Osaka 554-0022, Japan

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm051089s

Reference20 articles.

1. Hepatitis C virus infection is associated with the development of hepatocellular carcinoma.

2. A randomized controlled trial of pegylated interferon alpha-2a (40 KD) or interferon alpha-2a plus ribavirin and amantadine vs interferon alpha-2a and ribavirin in treatment-naive patients with chronic hepatitis C

3. Peginterferon α-2a Combination Therapies in Chronic Hepatitis C Patients Who Relapsed After or Had a Viral Breakthrough on Therapy with Standard Interferon α-2b Plus Ribavirin: A Pilot Study of Efficacy and Safety

4. Interferon for Decreasing the Incidence of Hepatocellular Carcinoma in Patients with Chronic Hepatitis C

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