Discovery of Novel 2-Aryl-4-benzoyl-imidazoles Targeting the Colchicines Binding Site in Tubulin As Potential Anticancer Agents-Reference-Cited by-同舟云学术

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Discovery of Novel 2-Aryl-4-benzoyl-imidazoles Targeting the Colchicines Binding Site in Tubulin As Potential Anticancer Agents

Published:2010-10-04 Issue:20 Volume:53 Page:7414-7427
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Chen Jianjun¹,Wang Zhao¹,Li Chien-Ming²³,Lu Yan¹,Vaddady Pavan K.¹,Meibohm Bernd¹,Dalton James T.²³,Miller Duane D.¹³,Li Wei¹

Affiliation:

1. Department of Pharmaceutical Sciences, University of Tennessee Health Science Center, Memphis, Tennessee 38163, United States

2. Division of Pharmaceutics, College of Pharmacy, The Ohio State University, Columbus, Ohio 43210, United States

3. GTx, Inc., Memphis, Tennessee 38163, United States

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm100884b

Reference33 articles.

1. Synthesis and antiproliferative activity of imidazole and imidazoline analogs for melanoma

2. Discovery of 4-Substituted Methoxybenzoyl-aryl-thiazole as Novel Anticancer Agents: Synthesis, Biological Evaluation, and Structure−Activity Relationships

3. Synthesis, formulation and in vitro evaluation of a novel microtubule destabilizer, SMART-100

4. Easy access to the family of thiazole N-oxides using HOF·CH3CN

5. Williams, D. A.; Lemke, T. L.Foye’s Principles of Medicinal Chemistry,5thed.Lippincott Williams & Wilkins:Philadelphia, 2002.

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