Chemoenzymatic Approaches toward Dechloroansamitocin P-3

Author:

Meyer Axel1,Brünjes Marco1,Taft Florian1,Frenzel Thomas1,Sasse Florenz1,Kirschning Andreas1

Affiliation:

1. Institut für Organische Chemie, Leibniz Universität Hannover, Schneiderberg 1B, 30167 Hannover, Germany, and Helmholtzzentrum für Infektionsforschung (HZI), Mascheroder Weg 1, 38124 Braunschweig, Germany

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Reference40 articles.

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3. Maytansinoids have also been isolated from two other plant families (Colubrina texensis;RhamnaceaeandTrewia nudiflora;Euphorbiaceae):  (a) Reider, P. J.; Roland, D. M. InThe Alkaloids; Brossi, A., Ed.; Academic Press:  New York, 1984; Vol. 23, pp 71−156. (b) Wani, M. C.; Taylor, H. L.; Wall, M. E.J. Chem. Soc.,Chem. Commun.1973, 390−390. (c) Powell, R. G.; Weisleder, D.; Smith, C. R., Jr.; Kozlowski, J.; Rohwedder, W. K.J. Am.Chem. Soc.1982,104, 4929−4934. (d) Powell, R. G.; Smith, C. R., Jr.; Plattner, R. D.; Jones, B. E.J. Nat. Prod.1983,46, 660−666. (e) Smith, C. R., Jr.; Powell, R. G. InAlkaloids; Pelletier, S. W., Ed.; John Wiley and Sons:  New York, 1984; Vol. 2, pp 149−204.

4. Ansamitocin, a group of novel maytansinoid antibiotics with antitumour properties from Nocardia

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