Evidence for a Functionally Relevant Rocaglamide Binding Site on the eIF4A–RNA Complex-Reference-Cited by-同舟云学术

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Evidence for a Functionally Relevant Rocaglamide Binding Site on the eIF4A–RNA Complex

Published:2013-05-07 Issue:7 Volume:8 Page:1519-1527
ISSN:1554-8929
Container-title:ACS Chemical Biology
language:en
Short-container-title:ACS Chem. Biol.

Author:

Sadlish Heather¹,Galicia-Vazquez Gabriela,Paris C. Gregory²,Aust Thomas¹,Bhullar Bhupinder¹,Chang Lena¹,Helliwell Stephen B.¹,Hoepfner Dominic¹,Knapp Britta¹,Riedl Ralph¹,Roggo Silvio¹,Schuierer Sven¹,Studer Christian¹,Porco John A.³,Pelletier Jerry,Movva N. Rao¹

Affiliation:

1. Novartis Institutes for BioMedical Research, Novartis Campus, CH-4056 Basel, Switzerland

2. Novartis Institutes for BioMedical Research, 250 Massachusetts Avenue Cambridge Massachusetts 02139, United States

3. Department of Chemistry, Center for Chemical Methodology and Library Development, Boston University, Boston, Massachusetts, United States

Publisher

American Chemical Society (ACS)

Subject

Molecular Medicine,General Medicine,Biochemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/cb400158t

Reference42 articles.

1. The Mechanism of Eukaryotic Translation Initiation: New Insights and Challenges

2. The Role of Translation Initiation Regulation in Haematopoiesis

3. Translational control in cancer

4. The biological and therapeutic relevance of mRNA translation in cancer

5. Cytostatic mechanism and antitumor potential of novel 1H-cyclopenta[b]benzofuran lignans isolated from Aglaiaelliptica

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1. Amidino-rocaglates (ADRs), a class of synthetic rocaglates, are potent inhibitors of SARS-CoV-2 replication through inhibition of viral protein synthesis;Antiviral Research;2024-10

2. DMDA-PatA mediates RNA sequence-selective translation repression by anchoring eIF4A and DDX3 to GNG motifs;Nature Communications;2024-09-02

3. Anti-tumor effects of the eIF4A inhibitor didesmethylrocaglamide and its derivatives in human and canine osteosarcomas;Scientific Reports;2024-08-20

4. Anti-tumor Effects of the eIF4A Inhibitor Didesmethylrocaglamide and Its Derivatives in Human and Canine Osteosarcomas;2024-06-14

5. Protein translation rate determines neocortical neuron fate;Nature Communications;2024-06-07

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