Small Molecule Inhibitors of the Neuropilin-1 Vascular Endothelial Growth Factor A (VEGF-A) Interaction-Reference-Cited by-同舟云学术

Small Molecule Inhibitors of the Neuropilin-1 Vascular Endothelial Growth Factor A (VEGF-A) Interaction

Published:2010-02-12 Issue:5 Volume:53 Page:2215-2226
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Jarvis Ashley¹,Allerston Charles K.²,Jia Haiyan³⁴,Herzog Birger³⁴,Garza-Garcia Acely⁵,Winfield Natalie¹,Ellard Katie¹,Aqil Rehan¹,Lynch Rosemary¹,Chapman Chris¹,Hartzoulakis Basil¹,Nally James¹,Stewart Mark¹,Cheng Lili³⁴,Menon Malini³⁴,Tickner Michelle³⁴,Djordjevic Snezana⁶,Driscoll Paul C.⁵,Zachary Ian⁴,Selwood David L.⁷

Affiliation:

1. Domainex Ltd. (NCE Discovery), 324 Cambridge Science Park, Cambridge CB4 0WG, U.K.

2. Ark Therapeutics, Structural and Molecular Biology, UCL, Gower Street, London WC1E 6BT, U.K.

3. Ark Therapeutics Ltd., Rayne Building, 5 University Street, London WC1E 6JJ, U.K.

4. Centre for Cardiovascular Biology and Medicine, BHF Laboratories at UCL, 5 University Street, London WC1E 6JJ, U.K.

5. Division of Molecular Structure, MRC National Institute for Medical Research, The Ridgeway, Mill Hill, London NW7 1AA, U.K.

6. Structural and Molecular Biology, UCL, Gower Street, London WC1E 6BT, U.K.

7. Biological and Medicinal Chemistry Group, Wolfson Institute for Biomedical Research, UCL, Gower Street, London WC1E 6BT, U.K.

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm901755g

Reference21 articles.

1. Neuropilins: structure, function and role in disease

2. Semaphorins command cells to move

3. Blocking Neuropilin-1 Function Has an Additive Effect with Anti-VEGF to Inhibit Tumor Growth

4. Reaching for high-hanging fruit in drug discovery at protein–protein interfaces

5. Predicting protein druggability

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