Synthesis of 4-[2-Aminoethyl(nitrosamino)]-1-pyridin-3-yl-butan-1-one, a New NNK Hapten for the Induction of N-Nitrosamine-Specific Antibodies-Reference-Cited by-同舟云学术

Synthesis of 4-[2-Aminoethyl(nitrosamino)]-1-pyridin-3-yl-butan-1-one, a New NNK Hapten for the Induction of N-Nitrosamine-Specific Antibodies

Published:2007-10-17 Issue:6 Volume:18 Page:2045-2053
ISSN:1043-1802
Container-title:Bioconjugate Chemistry
language:en
Short-container-title:Bioconjugate Chem.

Author:

Prodhomme Emmanuel J. F.¹,Ensch Corinne¹,Bouche Fabienne B.¹,Kaminski Thomas¹,Deroo Sabrina¹,Seck Pierre¹,Kirsch Gilbert¹,Muller Claude P.¹

Affiliation:

1. Institute of Immunology, Laboratoire National de Santé, 20A rue Auguste Lumière, L-1011 Luxembourg, Luxembourg, LIMBP, University Paul Verlaine - Metz, 1 boulevard Arago, F-57070 Metz, France, Laboratoire de Rétrovirologie, CRP-Santé, 84 rue Val Fleuri, L-1526 Luxembourg, Luxembourg, and University of Luxembourg, 162A avenue de la Faïencerie, L-1511 Luxembourg, Luxembourg

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Pharmaceutical Science,Pharmacology,Biomedical Engineering,Bioengineering,Biotechnology

Link

https://pubs.acs.org/doi/pdf/10.1021/bc070046i

Reference37 articles.

1. Biochemistry, Biology, and Carcinogenicity of Tobacco-Specific N-Nitrosamines

2. Metabolic Activation and Detoxification of Tobacco-Specific Nitrosamines–A Model for Cancer Prevention Strategies

3. Human cervical tissue metabolizes the tobacco-specific nitrosamine, 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone, via alpha-hydroxylation and carbonyl reduction pathways

4. Cytochrome P450 Enzymes as Catalysts of Metabolism of 4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanone, a Tobacco Specific Carcinogen

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