7-Azaindenoisoquinolines as Topoisomerase I Inhibitors and Potential Anticancer Agents-Reference-Cited by-同舟云学术

7-Azaindenoisoquinolines as Topoisomerase I Inhibitors and Potential Anticancer Agents

Published:2011-08-08 Issue:17 Volume:54 Page:6106-6116
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Kiselev Evgeny¹,DeGuire Sean¹,Morrell Andrew¹,Agama Keli²,Dexheimer Thomas S.²,Pommier Yves²,Cushman Mark¹

Affiliation:

1. Department of Medicinal Chemistry and Molecular Pharmacology, College of Pharmacy, and The Purdue Center for Cancer Research, Purdue University, West Lafayette, Indiana, 47907, United States

2. Laboratory of Molecular Pharmacology, Center for Cancer Research, National Cancer Institute, Bethesda, Maryland 20892-4255, United States

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm200719v

Reference40 articles.

1. Topoisomerase I inhibitors: camptothecins and beyond

2. Mechanism of action of eukaryotic DNA topoisomerase I and drugs targeted to the enzyme

3. Friction and torque govern the relaxation of DNA supercoils by eukaryotic topoisomerase IB

4. Crystal Structures of Human Topoisomerase I in Covalent and Noncovalent Complexes with DNA

5. Plant Antitumor Agents. I. The Isolation and Structure of Camptothecin, a Novel Alkaloidal Leukemia and Tumor Inhibitor from Camptotheca acuminata1,2

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