Structure-Based Optimization of Pyrazolo[3,4-d]pyrimidines as Abl Inhibitors and Antiproliferative Agents toward Human Leukemia Cell Lines-Reference-Cited by-同舟云学术

Structure-Based Optimization of Pyrazolo[3,4-d]pyrimidines as Abl Inhibitors and Antiproliferative Agents toward Human Leukemia Cell Lines

Published:2008-02-08 Issue:5 Volume:51 Page:1252-1259
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Manetti Fabrizio¹,Brullo Chiara¹,Magnani Matteo¹,Mosci Francesca¹,Chelli Beatrice¹,Crespan Emmanuele¹,Schenone Silvia¹,Naldini Antonella¹,Bruno Olga¹,Trincavelli Maria Letizia¹,Maga Giovanni¹,Carraro Fabio¹,Martini Claudia¹,Bondavalli Francesco¹,Botta Maurizio¹

Affiliation:

1. Dipartimento Farmaco Chimico Tecnologico, Università degli Studi di Siena, Via Alcide de Gasperi 2, I-53100, Siena, Italy, Dipartimento di Scienze Farmaceutiche, Università degli Studi di Genova, Viale Benedetto XV 3, I-16132, Genova, Italy, Dipartimento di Fisiologia, Sezione di Neuroimmunofisiologia, Università degli Studi di Siena, Via Aldo Moro, I-53100, Siena, Italy, Dipartimento di Psichiatria, Neurobiologia, Farmacologia e Biotecnologie, Università di Pisa, Via Bonanno 6, I-56126, Italy, and...

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm701240c

Reference29 articles.

1. A New Consistent Chromosomal Abnormality in Chronic Myelogenous Leukaemia identified by Quinacrine Fluorescence and Giemsa Staining

2. Chronic Myeloid Leukemia

3. Tyrosine Kinase Activity and Transformation Potency of bcr-abl Oncogene Products

4. Selective pyrrolo-pyrimidine inhibitors reveal a necessary role for Src family kinases in Bcr–Abl signal transduction and oncogenesis

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