Use of immobilized artificial membrane chromatography for drug transport applications††Abbreviations: blood-brain barrier, BBB; bovine brain microvessel endothelial cells, BBMEC; calculated log distribution coefficient (Pallas, CompuDrug, Budapest, Hungary), ClogD; calculated log partition coefficient, ClogP; capacity factor on an IAM column, k¢IAM; capacity factor on a reversed-phase column, k¢w; log distribution coefficient, log D; immobilized artificial membrane, IAM; nonsteroidal antiinflammatory, NSAID; octadecylsilicate, ODS; log octanol:water intrinsic partition coefficient, log P; phosphate-buffered saline, PBS; phosphatidylcholine, PC.

Author:

Stewart Barbra H.,Helen Chan O.

Publisher

American Geophysical Union (AGU)

Subject

Pharmaceutical Science

Reference53 articles.

1. Absorption of Drugs from the Rat Small Intestine;Schanker;J. Phar-macol. Exp. Ther.,1958

2. A Reevaluation of the Importance of Partition Coefficients in the Gastrointestinal Absorption of Nutrients;Houston;J. Pharmacol. Exp. Ther.,1974

3. Absorption Potential: Estimating the Fraction Absorbed for Orally Administered Compounds;Dressman;J. Pharm. Sci.,1985

4. Peptides and the Blood-Brain Barrier: Lipophilicity as a Predictor of Permeability;Banks;Brain Res. Bull.,1985

5. Relationship of Octanol/Water Partition Coefficient and Molecular Weight to Rat Brain Capillary Permeability;Levin;J. Med. Chem.,1980

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