Observation of an Acryloyl−Thiamin Diphosphate Adduct in the First Step of Clavulanic Acid Biosynthesis
Author:
Affiliation:
1. Departments of Biophysics and Chemistry, The Johns Hopkins University, Baltimore, Maryland 21218
Publisher
American Chemical Society (ACS)
Subject
Colloid and Surface Chemistry,Biochemistry,General Chemistry,Catalysis
Link
https://pubs.acs.org/doi/pdf/10.1021/ja076704r
Reference24 articles.
1. Industrial production of β-lactam antibiotics
2. New reactions in clavulanic acid biosynthesis
3. Origin of the β-Lactam Carbons in Clavulanic Acid from an Unusual Thiamine Pyrophosphate-Mediated Reaction
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