Design and Synthesis of Novel DFG-Out RAF/Vascular Endothelial Growth Factor Receptor 2 (VEGFR2) Inhibitors. 1. Exploration of [5,6]-Fused Bicyclic Scaffolds-Reference-Cited by-同舟云学术

Design and Synthesis of Novel DFG-Out RAF/Vascular Endothelial Growth Factor Receptor 2 (VEGFR2) Inhibitors. 1. Exploration of [5,6]-Fused Bicyclic Scaffolds

Published:2012-03-14 Issue:7 Volume:55 Page:3452-3478
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Okaniwa Masanori¹,Hirose Masaaki¹,Imada Takashi¹,Ohashi Tomohiro¹,Hayashi Youko¹,Miyazaki Tohru¹,Arita Takeo¹,Yabuki Masato¹,Kakoi Kazuyo¹,Kato Juran¹,Takagi Terufumi¹,Kawamoto Tomohiro¹,Yao Shuhei¹,Sumita Akihiko²,Tsutsumi Shunichirou²,Tottori Tsuneaki²,Oki Hideyuki¹,Sang Bi-Ching³,Yano Jason³,Aertgeerts Kathleen³,Yoshida Sei¹,Ishikawa Tomoyasu¹

Affiliation:

1. Pharmaceutical Research Division, Takeda Pharmaceutical Company Limited, 26-1, Muraoka-Higashi 2-Chome, Fujisawa, Kanagawa 251-8555, Japan

2. CMC Center, Takeda Pharmaceutical Company Limited, 17-85, Jusohonmachi 2-Chome, Yodogawa-ku, Osaka 532-8686, Japan

3. Structural Biology, Takeda California, Inc., 10410 Science Center Drive, San Diego, California 92121, United States

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm300126x

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