3-Amido Pyrrolopyrazine JAK Kinase Inhibitors: Development of a JAK3 vs JAK1 Selective Inhibitor and Evaluation in Cellular and in Vivo Models-Reference-Cited by-同舟云学术

3-Amido Pyrrolopyrazine JAK Kinase Inhibitors: Development of a JAK3 vs JAK1 Selective Inhibitor and Evaluation in Cellular and in Vivo Models

Published:2012-12-19 Issue:1 Volume:56 Page:345-356
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Soth Michael¹,Hermann Johannes C.¹,Yee Calvin¹,Alam Muzaffar¹,Barnett Jim W.²,Berry Pamela¹,Browner Michelle F.²,Frank Karl²,Frauchiger Sandra²,Harris Seth²,He Yang¹,Hekmat-Nejad Mohammad²,Hendricks Than²,Henningsen Robert²,Hilgenkamp Ramona¹,Ho Hoangdung²,Hoffman Ann¹,Hsu Pei-Yuan¹,Hu Dong-Qing¹,Itano Andrea²,Jaime-Figueroa Saul¹,Jahangir Alam²,Jin Sue¹,Kuglstatter Andreas¹,Kutach Alan K.²,Liao Cheng¹,Lynch Stephen¹,Menke John¹,Niu Linghao¹,Patel Vaishali¹,Railkar Aruna¹,Roy Douglas¹,Shao Ada²,Shaw David²,Steiner Sandra¹,Sun Yongliang¹,Tan Seng-Lai¹,Wang Sandra²,Vu Minh Diem¹

Affiliation:

1. Hoffmann-La Roche, 340 Kingsland Street, Nutley, New Jersey 07110, United States

2. Roche Palo Alto, 3431 Hillview Avenue, Palo Alto, California 94304, United States

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm301646k

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