Comparative Biodistribution and Pharmacokinetic Analysis of Cyclosporine-A in the Brain upon Intranasal or Intravenous Administration in an Oil-in-Water Nanoemulsion Formulation-Reference-Cited by-同舟云学术

Comparative Biodistribution and Pharmacokinetic Analysis of Cyclosporine-A in the Brain upon Intranasal or Intravenous Administration in an Oil-in-Water Nanoemulsion Formulation

Published:2015-03-31 Issue:5 Volume:12 Page:1523-1533
ISSN:1543-8384
Container-title:Molecular Pharmaceutics
language:en
Short-container-title:Mol. Pharmaceutics

Author:

Yadav Sunita¹²,Gattacceca Florence³,Panicucci Riccardo²,Amiji Mansoor M.¹

Affiliation:

1. Department of Pharmaceutical Sciences, School of Pharmacy, Northeastern University, Boston, Massachusetts 02115, United States

2. Novartis Institute of Biomedical Research, Cambridge, Massachusetts 02142, United States

3. IRCM, Institut de Recherche en Cancérologie de Montpellier, INSERM U1194, Montpellier University, Montpellier F-34298, France

Funder

National Institute of Neurological Disorders and Stroke

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Pharmaceutical Science,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/mp5008376

Reference32 articles.

1. The blood-brain barrier: Bottleneck in brain drug development

2. Biological effects of cyclosporin A: A new antilymphocytic agent

3. Neuronal localization of the cyclophilin A protein in the adult rat brain

4. A hydrogel composite system for sustained epi-cortical delivery of Cyclosporin A to the brain for treatment of stroke

5. Quantitative analysis of the olfactory pathway for drug delivery to the brain

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