Novel Synthesis of 3,4-Diarylisoxazole Analogues of Valdecoxib: Reversal Cyclooxygenase-2 Selectivity by Sulfonamide Group Removal-Reference-Cited by-同舟云学术

Novel Synthesis of 3,4-Diarylisoxazole Analogues of Valdecoxib: Reversal Cyclooxygenase-2 Selectivity by Sulfonamide Group Removal

Published:2004-08-26 Issue:20 Volume:47 Page:4881-4890
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Di Nunno Leonardo¹,Vitale Paola¹,Scilimati Antonio¹,Tacconelli Stefania¹,Patrignani Paola¹

Affiliation:

1. Dipartimento Farmaco-Chimico, Università di Bari, Via Orabona no. 4, 70125 Bari, Italy, and Dipartimento di Medicina e Scienze dell'Invecchiamento, Università degli Studi “G. D'Annunzio”, Via dei Vestini, 66100 Chieti, Italy

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm040782x

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