A Highly Concise and Convergent Synthesis of HCV Polymerase Inhibitor Deleobuvir (BI 207127): Application of a One-Pot Borylation–Suzuki Coupling Reaction-Reference-Cited by-同舟云学术

A Highly Concise and Convergent Synthesis of HCV Polymerase Inhibitor Deleobuvir (BI 207127): Application of a One-Pot Borylation–Suzuki Coupling Reaction

Published:2014-08-08 Issue:17 Volume:16 Page:4558-4561
ISSN:1523-7060
Container-title:Organic Letters
language:en
Short-container-title:Org. Lett.

Author:

Zhang Yongda¹,Lu Bruce Z.¹,Li Guisheng¹,Rodriguez Sonia¹,Tan Jonathan¹,Wei Han-Xun¹,Liu Jianxiu¹,Roschangar Frank¹,Ding Fei¹,Zhao Wenyi¹,Qu Bo¹,Reeves Diana¹,Grinberg Nelu¹,Lee Heewon¹,Heckmann Golo²,Niemeier Oliver²,Brenner Michael²,Tsantrizos Youla³,Beaulieu Pierre L.³,Hossain Azad¹,Yee Nathan¹,Farina Vittorio,Senanayake Chris H.¹

Affiliation:

1. Chemical Development, Boehringer Ingelheim Pharmaceuticals, Inc., 900 Ridgebury Road, Ridgefield, Connecticut 06877, United States

2. Boehringer Ingelheim GmbH & Co KG, Binger Strasse 173, 55216 Ingelheim am Rhein, Germany

3. Research and Development, Boehringer Ingelheim (Canada) Ltd., 2100 Cunard Street, Laval, Quebec H7S 2G5, Canada

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/ol5021114

Reference36 articles.

1. Introduction: A smouldering public-health crisis