Discovery of Potent and Selective Inhibitors of Human Platelet-Type 12- Lipoxygenase-Reference-Cited by-同舟云学术

Discovery of Potent and Selective Inhibitors of Human Platelet-Type 12- Lipoxygenase

Published:2011-07-08 Issue:15 Volume:54 Page:5485-5497
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Kenyon Victor¹,Rai Ganesha²,Jadhav Ajit²,Schultz Lena²,Armstrong Michelle¹,Jameson J. Brian¹,Perry Steven¹,Joshi Netra¹,Bougie James M.²,Leister William²,Taylor-Fishwick David A.³,Nadler Jerry L.³,Holinstat Michael⁴,Simeonov Anton²,Maloney David J.²,Holman Theodore R.¹

Affiliation:

1. Department of Chemistry and Biochemistry, University of California, Santa Cruz, 250 Physical Sciences Building, Santa Cruz, California 95064, United States

2. NIH Chemical Genomics Center, National Human Genome Research Institute, National Institutes of Health, 9800 Medical Center Drive, MSC 3370 Bethesda, Maryland 20892-3370, United States

3. Department of Internal Medicine, Strelitz Diabetes Center, Eastern Virginia Medical School, Norfolk, Virginia 23501-1980, United States

4. Department of Medicine, Cardeza Foundation for Hematologic Research, Thomas Jefferson University, Philadelphia, Pennsylvania 19107, United States

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm2005089

Reference91 articles.

1. New insights from spectroscopy into the structure/function relationships of lipoxygenases

2. 5-LIPOXYGENASE

3. Arachidonic Acid Metabolites in the Cardiovascular System: The Role of Lipoxygenase Isoforms in Atherogenesis With Particular Emphasis on Vascular Remodeling