Discovery of AZD6642, an Inhibitor of 5-Lipoxygenase Activating Protein (FLAP) for the Treatment of Inflammatory Diseases-Reference-Cited by-同舟云学术

Discovery of AZD6642, an Inhibitor of 5-Lipoxygenase Activating Protein (FLAP) for the Treatment of Inflammatory Diseases

Published:2014-12-22 Issue:2 Volume:58 Page:897-911
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Lemurell Malin¹,Ulander Johan¹,Winiwarter Susanne¹,Dahlén Anders¹,Davidsson Öjvind¹,Emtenäs Hans¹,Broddefalk Johan¹,Swanson Marianne¹,Hovdal Daniel¹,Plowright Alleyn T.¹,Pettersen Anna¹,Rydén-Landergren Marie¹,Barlind Jonas¹,Llinas Antonio¹,Herslöf Margareta¹,Drmota Tomas¹,Sigfridsson Kalle¹,Moses Sara¹,Whatling Carl¹

Affiliation:

1. Cardiovascular & Metabolic Diseases iMed, ‡Respiratory, Inflammation & Autoimmune Diseases iMed, §Drug Safety & Metabolism, and ∥Pharmaceutical Development, AstraZeneca, Pepparedsleden 1, Mölndal, 43183, Sweden

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm501531v

Reference34 articles.

1. Cell Biology of the 5-Lipoxygenase Pathway

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4. Leukotriene receptor antagonists pranlukast and montelukast for treating asthma

5. The potential link between atherosclerosis and the 5-lipoxygenase pathway: investigational agents with new implications for the cardiovascular field

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