Hydroxyethylene Sulfones as a New Scaffold To Address Aspartic Proteases: Design, Synthesis, and Structural Characterization-Reference-Cited by-同舟云学术

Hydroxyethylene Sulfones as a New Scaffold To Address Aspartic Proteases: Design, Synthesis, and Structural Characterization

Published:2005-09-16 Issue:21 Volume:48 Page:6607-6619
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Specker Edgar¹,Böttcher Jark¹,Heine Andreas¹,Sotriffer Christoph A.¹,Lilie Hauke¹,Schoop Andreas¹,Müller Gerhard¹,Griebenow Nils¹,Klebe Gerhard¹

Affiliation:

1. Institut für Pharmazeutische Chemie, Philipps-Universität Marburg, Marbacher Weg 6, D-35032 Marburg, Germany, Institut für Biotechnologie, Martin-Luther-Universität Halle-Wittenberg, Kurt-Mothes-Strasse 3, D-06120 Halle (Saale), Germany, Boehringer Ingelheim, Wien, Austria, Axxima Pharmaceuticals AG, München, Germany, and Bayer AG, Elberfeld, Germany

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm050224y

Reference32 articles.

1. Structural Studies of Ribonuclease. XIV. Tryptic Hydrolysis of Ribonuclease in Propyl Alcohol Solution*

2. Human liver cathepsin D

3. Structure and inhibition of plasmepsin II, a hemoglobin-degrading enzyme from Plasmodium falciparum.

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